ELK Biotechnology PCDG9 rabbit pAb
인간, 랫트, 마우스에 반응하는 PCDG9 단백질에 대한 토끼 폴리클로날 항체. WB 실험에 적합하며 1:500~1:2000 희석 권장. 인간 PCDG9 유래 펩타이드로 면역화됨. 세포막 단일 통과형 I 막단백질 표적. -20°C에서 1년 보관 가능.
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ELK Biotechnology PCDG9 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | PCDG9 rabbit pAb |
| Applications | WB |
| Recommended Dilutions | WB 1:500–2000 |
| Immunogen | Synthesized peptide derived from human PCDG9 (AA range: 354–404) |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 56107 |
| Human Swiss-Prot No | Q9Y5G4 |
| Cellular localization | Cell membrane; Single-pass type I membrane protein |
| Species Reactivity | Human, Rat, Mouse |
Background
This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression.
The gamma gene cluster includes 22 genes divided into 3 subfamilies:
- Subfamily A: 12 genes
- Subfamily B: 7 genes and 2 pseudogenes
- Subfamily C: 3 genes
Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
(Provided by RefSeq, Jul 2008)
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