ELK Biotechnology PCDGF rabbit pAb
Human PCDGF 단백질을 인식하는 rabbit polyclonal antibody로, WB, ELISA, IHC에 사용 가능. 고순도 IgG 형태로 1 mg/ml 농도, -20°C에서 1년 보관. 세포막 단일 통과형 단백질 검출에 적합.
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ELK Biotechnology PCDGF rabbit pAb
제품 개요
PCDGF rabbit polyclonal antibody는 인간 PCDGF 단백질을 인식하도록 제작된 항체로, 다양한 생물학적 연구에 활용됩니다. WB, ELISA, IHC 등 여러 응용 분야에서 높은 특이성과 재현성을 제공합니다.
제품 사양
| 항목 | 내용 |
|---|---|
| Product name | PCDGF rabbit pAb |
| Applications | WB; ELISA; IHC |
| Recommended Dilutions | WB 1:500–2000; IHC-p 1:50–300; ELISA 1:2000–20000 |
| Immunogen | Synthesized peptide derived from human PCDGF (AA range: 236–286) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 56102 |
| Human Swiss-Prot No. | Q9Y5G1 |
| Cellular localization | Cell membrane; Single-pass type I membrane protein |
| Species Reactivity | Human; Rat; Mouse |
Background
This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies:
- Subfamily A contains 12 genes
- Subfamily B contains 7 genes and 2 pseudogenes
- Subfamily C contains 3 genes
Each variable region exon encodes the extracellular region, including 6 cadherin ectodomains and a transmembrane region, while the constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins likely play a critical role in establishing and maintaining specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
[Provided by RefSeq, Jul 2008]
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