ELK Biotechnology PCDGF rabbit pAb

ELK Biotechnology PCDGF rabbit pAb

제품 개요

PCDGF rabbit polyclonal antibody는 인간 PCDGF 단백질을 인식하도록 제작된 항체로, 다양한 생물학적 연구에 활용됩니다. WB, ELISA, IHC 등 여러 응용 분야에서 높은 특이성과 재현성을 제공합니다.

제품 사양

Background

This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies:

• Subfamily A contains 12 genes
• Subfamily B contains 7 genes and 2 pseudogenes
• Subfamily C contains 3 genes

Each variable region exon encodes the extracellular region, including 6 cadherin ectodomains and a transmembrane region, while the constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins likely play a critical role in establishing and maintaining specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
[Provided by RefSeq, Jul 2008]