ELK Biotechnology PDGF Receptor α (phospho-Tyr1018) rabbit pAb
PDGF Receptor α (phospho-Tyr1018) rabbit pAb는 인간 및 생쥐 시료에서 PDGFRα 인산화 형태를 검출하기 위한 고품질 폴리클로날 항체입니다. WB, ELISA, IHC에 적합하며 세포막 및 골지체에 위치한 단백질 분석에 유용합니다. -20°C에서 1년간 안정적으로 보관 가능합니다.
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PDGF Receptor α (phospho-Tyr1018) rabbit pAb
제품 개요
PDGF Receptor α (phospho-Tyr1018) rabbit pAb는 혈소판 유래 성장인자 수용체 알파의 인산화된 형태를 인식하는 폴리클로날 항체로, 세포 신호 전달 및 암 연구 등 다양한 생명과학 연구에 사용됩니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product Name | PDGF Receptor α (phospho-Tyr1018) rabbit pAb |
| Alternative Names | Platelet-derived growth factor receptor alpha (PDGF-R-alpha), PDGFR-alpha, EC 2.7.10.1, Alpha platelet-derived growth factor receptor, Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, CD140a antigen, Platelet-derived growth factor alpha receptor, PDGFR-2, CD antigen CD140a |
| Applications | WB; ELISA; IHC |
| Recommended Dilutions | WB 1:500–2000; IHC-p 1:50–300; ELISA 1:2000–20000 |
| Immunogen | Synthesized phospho peptide around human PDGF Receptor α (Tyr1018) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 180 kD |
| GeneID (Human) | 5156 |
| Human Swiss-Prot No | P16234 |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein; Cell projection (cilium); Golgi apparatus |
| Species Reactivity | Human; Mouse |
Background
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors act as mitogens for cells of mesenchymal origin. The specific growth factor bound to a receptor monomer determines whether the receptor forms a homodimer or heterodimer with PDGF receptor alpha and beta subunits. Research indicates involvement in organ development, wound healing, and tumor progression. Mutations are linked to idiopathic hypereosinophilic syndrome, gastrointestinal stromal tumors, and various cancers. (RefSeq, Mar 2012)
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