ELK Biotechnology PDGF Receptor β (phospho-Tyr1009) rabbit pAb
PDGF Receptor β (phospho-Tyr1009) rabbit polyclonal antibody로, 세포막 단백질 인산화 형태 검출에 적합합니다. WB 및 IHC에 사용 가능하며, 인간과 마우스 시료에 반응합니다. 세포 신호전달, 종양 연구 및 조직 발달 연구에 활용됩니다.
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PDGF Receptor β (phospho-Tyr1009) Rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | PDGF Receptor β (phospho-Tyr1009) rabbit pAb |
| Alternative Names | Platelet-derived growth factor receptor alpha (PDGF-R-alpha), PDGFR-alpha, EC 2.7.10.1, Alpha platelet-derived growth factor receptor, Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, CD140a antigen, Platelet-derived growth factor alpha receptor, Platelet-derived growth factor receptor 2, PDGFR-2, CD antigen CD140a |
| Applications | WB; IHC |
| Recommended Dilutions | WB 1:500–2000; IHC-p 1:50–300 |
| Immunogen | Synthesized phospho peptide around human PDGF Receptor β (Tyr1009) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 180 kD |
| Gene ID (Human) | 5156 |
| Human Swiss-Prot No. | P16234 |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein; Cell projection, cilium; Golgi apparatus |
| Species Reactivity | Human; Mouse |
Background
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor (PDGF) family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both PDGF receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and various other cancers.
[Provided by RefSeq, Mar 2012]
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