ELK Biotechnology PRPC rabbit pAb
PRPC rabbit pAb는 인간, 랫, 마우스에서 반응하는 폴리클로날 항체로 WB 분석에 적합합니다. 합성 펩타이드(AA 81–131)를 면역원으로 사용하며, 고순도 IgG 형태로 제공됩니다. -20°C 보관 시 1년 안정성을 유지합니다.
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제품명
PRPC rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB |
| Recommended Dilutions | WB 1:500–2000 |
| Immunogen | Synthesized peptide derived from human PRPC (AA range: 81–131) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 5554 |
| Human Swiss-Prot No | P02810 |
| Cellular Localization | Secreted |
| Species Reactivity | Human, Rat, Mouse |
Background
This gene encodes a member of the heterogeneous family of proline-rich salivary glycoproteins. The encoded preproprotein undergoes proteolytic processing to generate one or more mature isoforms before secretion from the parotid and submandibular/sublingual glands. Multiple distinct alleles of this locus including the parotid isoelectric-focusing variant slow (PIF-s), the parotid acidic protein (Pa), and the double band slow (Db-s) isoforms have been characterized. The reference genome encodes the Db-s allele. Certain alleles of this gene are associated with susceptibility to dental caries. This gene is located in a cluster of closely related salivary proline-rich proteins on chromosome 12. Co-transcription of this gene with adjacent genes has been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2015]
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