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ELK Biotechnology PSMD1 rabbit pAb
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PSMD1 단백질을 인식하는 토끼 폴리클로날 항체로, WB 실험에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, -20°C에서 1년간 보관 가능합니다. 1 mg/ml 농도의 IgG 형태로 제공됩니다.
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- pk
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ELK Biotechnology ES13882-100UL PSMD1 rabbit pAb, 100UL pk판매 단위 pk ·
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402,000원VAT 포함 442,200원
ELK Biotechnology ES13882-50UL PSMD1 rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology PSMD1 rabbit pAb
PSMD1 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | PSMD1 rabbit pAb |
| Alternative Names | 26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2), 26S proteasome regulatory subunit S1, 26S proteasome subunit p112 |
| Applications | WB |
| Recommended Dilutions | WB 1:500–2000 |
| Immunogen | Synthesized peptide derived from human PSMD1 (AA 192–242) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 105 kDa |
| Gene ID (Human) | 5707 |
| Human Swiss-Prot No. | Q99460 |
| Species Reactivity | Human, Mouse, Rat |
| Cellular Localization | Proteasome complex, nucleus, nucleoplasm, cytosol, proteasome regulatory particle (base subcomplex), membrane (integral component), proteasome accessory complex, proteasome storage granule, extracellular exosome |
Background
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of two complexes: a 20S core and a 19S regulator.
- The 20S core consists of four rings of 28 non-identical subunits (two rings of 7 alpha subunits and two rings of 7 beta subunits).
- The 19S regulator comprises a base (6 ATPase subunits and 2 non-ATPase subunits) and a lid (up to 10 non-ATPase subunits).
Proteasomes are abundant in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal pathway.
A modified form, the immunoproteasome, plays an essential role in processing class I MHC peptides.
This gene encodes the largest non-ATPase subunit of the 19S regulator lid, responsible for substrate recognition and binding. Alternatively spliced transcript variants have been identified for this gene.
(Information provided by RefSeq, Jul 2010)
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