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ELK Biotechnology Rev-erbα (phospho-Ser55/59) rabbit pAb
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Rev-erbα 단백질의 Ser55/59 인산화 형태를 인식하는 rabbit polyclonal antibody. WB 및 IHC에 적합하며, 핵과 세포질에서 발현되는 Rev-erbα의 위치 연구에 활용 가능. 고순도 IgG, 1 mg/ml 농도, -20°C에서 1년 보관.
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- pk
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ELK Biotechnology ES13420-100UL Rev-erbα (phospho-Ser55/59) rabbit pAb, 100UL pk판매 단위 pk ·
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402,000원VAT 포함 442,200원
ELK Biotechnology ES13420-50UL Rev-erbα (phospho-Ser55/59) rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology Rev-erbα (phospho-Ser55/59) rabbit pAb
Rev-erbα (phospho-Ser55/59) Rabbit Polyclonal Antibody
제품 정보
| 항목 | 내용 |
|---|---|
| Product Name | Rev-erbα (phospho-Ser55/59) rabbit pAb |
| Alternative Names | Nuclear receptor subfamily 1 group D member 1 (Rev-erbA-alpha), V-erbA-related protein 1, EAR-1 |
| Applications | WB; IHC |
| Recommended Dilutions | WB: 1:500–2000; IHC-p: 1:50–300 |
| Immunogen | Synthesized phospho peptide around human Rev-erbα (Ser55 and 59) |
| Host Species | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 67 kDa |
| Gene ID (Human) | 9572 |
| Human Swiss-Prot No. | P20393 |
| Species Reactivity | Human; Rat; Mouse |
| Cellular Localization | Nucleus, Cytoplasm, Cell projection (dendrite, dendritic spine). Localizes to cytoplasm, dendrites, and dendritic spine in the presence of OPHN1. Predominantly nuclear at ZT8 and cytoplasmic at ZT20. Phosphorylation by CSNK1E enhances cytoplasmic localization. |
Background
This gene encodes a transcription factor that is a member of the nuclear receptor subfamily 1. The encoded protein is a ligand-sensitive transcription factor that negatively regulates the expression of core clock proteins. In particular, this protein represses the circadian clock transcription factor aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL). It may also regulate genes involved in metabolic, inflammatory, and cardiovascular processes.
[Provided by RefSeq, Jan 2013]
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