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ELK Biotechnology RFX6 rabbit pAb
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ELK Biotechnology RFX6 rabbit pAb

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RFX6 단백질을 인식하는 토끼 다클론 항체로, WB, ELISA, IHC에 적합. 인간 및 생쥐 시료에 반응하며, β세포 분화 관련 연구에 유용. -20°C에서 1년 보관 가능.

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pk
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ELK Biotechnology ES13408-100UL RFX6 rabbit pAb, 100UL pk판매 단위 pk ·
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402,000원VAT 포함 442,200원
ELK Biotechnology ES13408-50UL RFX6 rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology RFX6 rabbit pAb

RFX6 rabbit pAb

제품 정보

항목 내용
Product name RFX6 rabbit pAb
Applications WB; ELISA; IHC
Recommended Dilutions WB 1:500–2000; IHC-p 1:50–300; ELISA 1:2000–20000
Immunogen Synthesized peptide derived from human RFX6 (AA range: 264–314)
Host Rabbit
Storage -20°C / 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
GeneID (Human) 222546
Human Swiss-Prot No Q8HWS3
Cellular Localization Nucleus
Species Reactivity Human; Mouse

Background

The nuclear protein encoded by this gene is a member of the regulatory factor X (RFX) family of transcription factors. Studies in mice suggest that this gene is specifically required for the differentiation of islet cells for the production of insulin, but not for the differentiation of pancreatic polypeptide-producing cells. It regulates the transcription factors involved in beta-cell maturation and function, thus restricting the expression of beta-cell differentiation and specification genes. Mutations in this gene are associated with Mitchell-Riley syndrome, characterized by neonatal diabetes with pancreatic hypoplasia, duodenal and jejunal atresia, and gall bladder agenesis.
[provided by RefSeq, Sep 2010]

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