ELK Biotechnology RIP3 (phospho-Ser227) rabbit pAb
RIP3 (phospho-Ser227) rabbit pAb은 인간 RIP3 단백질의 Ser227 인산화 형태를 인식하는 폴리클로날 항체입니다. WB, ELISA, IHC에 적합하며 세포질 및 핵 내 RIP3 검출에 유용합니다. 고순도 IgG, 안정적 저장(-20°C, 1년) 가능.
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RIP3 (phospho-Ser227) rabbit pAb
제품 개요
RIP3 (phospho-Ser227) rabbit pAb은 인간 RIP3 단백질의 Ser227 인산화 부위를 인식하는 폴리클로날 항체로, 세포 내 신호전달 및 세포사멸 관련 연구에 활용됩니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | RIP3 (phospho-Ser227) rabbit pAb |
| Alternative Names | Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1); RIP-like protein kinase 3; Receptor-interacting protein 3; RIP-3 |
| Applications | WB; ELISA; IHC |
| Recommended Dilutions | WB: 1:500–2000; IHC-p: 1:50–300; ELISA: 1:2000–20000 |
| Immunogen | Synthesized phospho peptide around human RIP3 (Ser227) |
| Host | Rabbit |
| Storage Conditions | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 56–70 kD |
| Gene ID (Human) | 11035 |
| Human Swiss-Prot No. | Q9Y572 |
| Cellular Localization | Cytoplasm, cytosol, nucleus. Mainly cytoplasmic; present in the nucleus in response to influenza A virus (IAV) infection. |
| Species Reactivity | Human |
Background
The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
[provided by RefSeq, Jul 2008]
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