Thermo Fisher Scientific SCP2 Monoclonal Antibody (OTI1D2), TrueMAB
SCP2 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot 및 IHC(파라핀 절편) 분석에 적합합니다. 인간 시료에 반응하며, 고순도 친화 크로마토그래피로 정제되었습니다. 안정한 액상 형태로 -20°C에서 보관 가능합니다.
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- TA507248
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D2 |
| Immunogen | Full length human recombinant protein of human SCP2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from two independently regulated promoters.
The transcript from the proximal promoter encodes the longer SCPx protein, while the distal promoter encodes the shorter SCP2 protein, sharing a common C-terminus.
Evidence suggests:
- SCPx: peroxisome-associated thiolase involved in oxidation of branched chain fatty acids
- SCP2: intracellular lipid transfer protein
This gene is highly expressed in organs involved in lipid metabolism and may play a role in Zellweger syndrome, characterized by peroxisome deficiency and impaired bile acid synthesis.
Alternative splicing produces multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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