Thermo Fisher Scientific LMP2 Polyclonal Antibody
Thermo Fisher Scientific의 LMP2 Polyclonal Antibody는 Human, Mouse, Rat에 반응하며 WB, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. Rabbit IgG 기반으로 제작된 액상 항체로, Protein A로 정제되어 높은 순도를 제공합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Proteasome 20S LMP2, amino acids 101–219 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure composed of 4 rings of 28 non-identical subunits: 2 rings of 7 alpha subunits and 2 rings of 7 beta subunits. Proteasomes are widely distributed throughout eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent process within a non-lysosomal pathway.
A modified form, the immunoproteasome, plays an essential role in processing class I MHC peptides. The gene encoding LMP2 belongs to the proteasome B-type (T1B) family and is located in the class II region of the MHC. Proteolytic processing is required to generate a mature subunit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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