Thermo Fisher Scientific Mono-Methyl-HIST1H2BC (Lys23) Polyclonal Antibody
Rabbit 폴리클로날 항체로, Human HIST1H2BC (Lys23) 단일 메틸화 형태를 인식. ICC/IF 및 ELISA에 적합하며 항원 친화 크로마토그래피로 정제됨. PBS/glycerol 버퍼에 보관, 연구용으로만 사용.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:10–1:100
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from Human Histone H2B type 1-C/E/F/G/I protein (17–28 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.14 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS (pH 7.4) with 50% glycerol |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2915010 |
Product Specific Information
Antibody tested in Indirect ELISA.
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of eukaryotic chromosomal fiber. Two molecules of each core histone (H2A, H2B, H3, and H4) form an octamer around which approximately 146 bp of DNA is wrapped, forming nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes, contributing to chromatin compaction. HIST1H2BC encodes a replication-dependent histone H2B variant with antibacterial and antifungal activity. The gene is intronless, lacks a polyA tail, and is located in the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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