Thermo Fisher Scientific EID3 Polyclonal Antibody
인간 EID3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. IHC(P) 및 ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 0.1 mg/mL 농도, 4°C 또는 -20°C 보관.
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- PA563712
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Thermo Fisher Scientific EID3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human EID3. Recombinant protein control fragment (Product #RP-101962) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640951 |
Product Specific Information
Immunogen sequence:
PDKLSDCDDS IALSFWKAIE KEATSWMVKA ETFHFVFGSF KLERSAPKPR LEHQKKVRKM EENGNMPTKL QKLDLSSYPE A
Highest antigen sequence identity to the following orthologs:
- Mouse: 60%
- Rat: 32%
Target Information
EID3 is a tissue-specific component of the SMC5-SMC6 complex, which is involved in the repair of DNA double-strand breaks by homologous recombination. This complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. It is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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