Thermo Fisher Scientific SLC30A8 Polyclonal Antibody
SLC30A8 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Western Blot 및 IHC(Paraffin)에 최적화됨. Human 시료 반응성, 1 mg/mL 농도, 항원 친화 크로마토그래피로 정제됨. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide corresponding to 14 amino acids near the amino terminus of human SLC30A8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2890350 |
Product Specific Information
Positive controls that may be used include: Human Pancreas Tissue Lysate
Target Information
Slc30A8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. It is highly expressed in the pancreas, particularly in islets of Langerhans, and co-localizes with insulin in the secretory granules of insulin-secreting INS-1 cells.
Allelic variants of Slc30A8 are major genetic risk factors for Type 2 diabetes, but no association has been found with Type 1 diabetes. Expression in β-cells is influenced by cytokines such as IFN-γ and IL-1β.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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