Thermo Fisher Scientific APLP1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 285-490 of human APLP1 (NP_0051571) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:APLP1,uniProtId:P51693-1,ncbiNodeId:9606,antigenRange:285-490,antigenLength:650,antigenImageFileName:PA5-109399_APLP1_P51693-1_Rabbit.svg,antigenImageFileNamePDP:PA5-109399_APLP1_P51693-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.09 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2854810

Product Specific Information

Immunogen sequence: TPTPRPTDGV DIYFGMPGEI SEHEGFLRAK MDLEERRMRQ INEVMREWAM ADNQSKNLPK ADRQALNEHF QSILQTLEEQ VSGERQRLVE THATRVIALI NDQRRAALEG FLAALQADPP QAERVLLALR RYLRAEQKEQ RHTLRHYQHV AAVDPEKAQQ MRFQVHTHLQ VIEERVNQSL GLLDQNPHLA QELRPQIQEL LHSEHL

Target Information

This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.