Thermo Fisher Scientific APLP1 Polyclonal Antibody
APLP1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF, ELISA에 사용 가능. 인간, 생쥐, 랫트 반응성. 고순도 Affinity Chromatography 정제. 연구용으로만 사용.
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Thermo Fisher Scientific APLP1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 285–490 of human APLP1 (NP_005157.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.09 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2854810 |
Product Specific Information
Immunogen sequence:
TPTPRPTDGV DIYFGMPGEI SEHEGFLRAK MDLEERRMRQ INEVMREWAM ADNQSKNLPK ADRQALNEHF QSILQTLEEQ VSGERQRLVE THATRVIALI NDQRRAALEG FLAALQADPP QAERVLLALR RYLRAEQKEQ RHTLRHYQHV AAVDPEKAQQ MRFQVHTHLQ VIEERVNQSL GLLDQNPHLA QELRPQIQEL LHSEHL
Target Information
This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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