Thermo Fisher Scientific NORE1 Polyclonal Antibody
NORE1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 최적화되어 있습니다. 인간, 쥐, 생쥐 간 100% 보존된 RA 도메인 서열을 기반으로 제작되었습니다. 암 억제 관련 연구 및 Ras 신호전달 경로 분석에 유용합니다.
- 카탈로그번호
- RA19038-100UG
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Residues 313–329 [DNPQKFALFKRIHKDGQ] of the NORE1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Product Specific Information
The immunogen sequence is located in the RA domain of NORE1 and is 100% conserved among human, rat, and mouse.
Target Information
This gene belongs to the Ras association domain family and functions as a tumor suppressor. It is inactivated in various cancers. The encoded protein localizes to centrosomes and microtubules, associating with GTP-activated forms of Ras, Rap1, and other Ras-like small GTPases. It regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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