Thermo Fisher Scientific MX2 Polyclonal Antibody
Human MX2 단백질을 표적으로 하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:200~1:500 희석 비율로 검증됨. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보관. 세포 내 MX2 단백질 연구 및 항바이러스 기전 분석에 적합.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MX2. Recombinant protein control fragment (Product #RP-95904) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790288 |
Product Specific Information
Immunogen sequence:
PYRRRSQFSS RKYLKKEMNS FQQQPPPFGT VPPQMMFPPN WQGAEKDAAF LAKDFNFLTL NNQPPPGNRS QPRAMG
Target Information
Members of the Dynamin family include GTPase, microtubule-associated proteins involved in cellular trafficking such as microtubule bundling and endocytosis.
Mx1 (MxA), an interferon-induced protein, confers resistance to influenza A and vesicular stomatitis virus (VSV), suggesting an antiviral role.
Mx1 shares 63% identity with Mx2 (MxB), which lacks antiviral activity and localizes to the cytoplasmic face of nuclear pores.
Mx2 expression is not interferon-dependent and may regulate nuclear import efficiency and kinetics.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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