
Thermo Fisher Scientific NFE2 Polyclonal Antibody
Human, Mouse, Rat에 반응하는 NFE2 폴리클로날 항체로 Western blot에 적합. Rabbit IgG로 제작되었으며, 합성 펩타이드 면역원 사용. 액상 형태, 1 mg/mL 농도, PBS/glycerol 버퍼에 저장. 적혈구 및 거핵세포 분화 관련 연구에 활용 가능.
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:500–1:2,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human NFE2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2692183 |
Product Specific Information
Predicted to react with Mouse and Rat samples.
Target Information
Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation.
Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR).
This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters.
Requires MAFK or other small MAF proteins for binding to the NF-E2 motif.
May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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