ELK Biotechnology EPS8 rabbit pAb
Human 및 Mouse 시료에 반응하는 EPS8 rabbit polyclonal antibody. WB 및 ELISA에 적합하며, EGFR pathway 관련 단백질 검출에 유용. 1 mg/ml 농도, -20°C에서 1년 보관 가능. 세포질 및 세포막 돌기 등 다양한 세포 부위에서 발현 확인.
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제품명
EPS8 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human protein at AA range: 130–210 |
| Species Reactivity | Human; Mouse |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 90 kD |
| Gene ID (Human) | 2059 |
| Human Swiss-Prot No. | Q12929 |
| Storage | -20°C / 1 year |
| Host | Rabbit |
세포 내 위치 (Cellular Localization)
Cytoplasm, cell cortex, cell projection (ruffle membrane, growth cone, stereocilium), cell junction (synapse, synaptosome).
Localizes at the tips of the stereocilia of the inner and outer hair cells (By similarity).
Localizes to the midzone of dividing cells.
배경 (Background)
This gene encodes a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determined. Highly similar proteins in other organisms are involved in the transduction of signals from Ras to Rac and growth factor-mediated actin remodeling. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
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