ELK Biotechnology NR2C1 rabbit pAb
NR2C1 단백질을 인식하는 토끼 폴리클로날 항체로, WB와 ELISA에 사용 가능. 인간, 마우스, 랫트 시료에 반응하며, 고순도 IgG 형태로 제공. 핵 내 위치 단백질 검출에 적합하며 -20°C에서 1년 보관 가능.
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NR2C1 rabbit pAb
공급업체: ELK Biotechnology
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | NR2C1 rabbit pAb |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human protein (AA range: 40–120) |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 66 kD |
| GeneID (Human) | 7181 |
| Human Swiss-Prot No | P13056 |
| Species Reactivity | Human; Mouse; Rat |
| Cellular Localization | Nucleus, PML body. Recruited by HDAC3 after all-trans retinoic acid stimulated MAPK1-mediated Thr-223 phosphorylation, to PML bodies for subsequent sumoylation. |
| Storage | -20°C / 1 year |
Background
This gene encodes a nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily.
This protein belongs to a large family of ligand-inducible transcription factors that regulate gene expression by binding to specific DNA sequences within promoters of target genes.
Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these variants has not been determined.
[provided by RefSeq, Jul 2008]
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