ELK Biotechnology DDR1 antibody
DDR1 단백질을 인식하는 rabbit polyclonal antibody로, WB 및 ELISA에 적합합니다. 인간 DDR1 유래 합성 펩타이드 면역원 사용. 세포막 및 분비형 isoform 검출 가능. -20°C에서 1년간 안정적으로 보관 가능.
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DDR1 Antibody
제품 개요
ELK Biotechnology의 DDR1 antibody는 인간 DDR1 단백질을 인식하는 rabbit polyclonal 항체입니다. 세포막 및 분비형 isoform을 검출할 수 있으며, WB와 ELISA 실험에 적합합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | DDR1 antibody |
| Alternative Names | Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a) |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:10000–20000 |
| Immunogen | Synthesized peptide derived from human DDR1 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 130 kD |
| GeneID (Human) | 780 |
| Human Swiss-Prot No | Q08345 |
| Cellular Localization | [Isoform 1]: Cell membrane; Single-pass type I membrane protein. [Isoform 2]: Cell membrane; Single-pass type I membrane protein. [Isoform 3]: Secreted. [Isoform 4]: Cell membrane; Single-pass type I membrane protein. |
| Species Reactivity | Human; Mouse; Rat |
Background
Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation, and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it is significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
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