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ELK Biotechnology Tyrosine Hydroxylase rabbit pAb
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ELK Biotechnology Tyrosine Hydroxylase rabbit pAb

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Tyrosine Hydroxylase rabbit pAb는 도파민 합성의 핵심 효소를 타깃으로 하는 폴리클로날 항체입니다. WB 및 ELISA에 적합하며, 사람·마우스·랫트 시료에 반응합니다. 고순도 IgG 형태로 제공되며, 장기 보관이 가능합니다.

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pk
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ELK Biotechnology ES8886-100UL Tyrosine Hydroxylase rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES8886-50UL Tyrosine Hydroxylase rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology Tyrosine Hydroxylase rabbit pAb

Tyrosine Hydroxylase rabbit pAb

제품 정보

항목 내용
Product name Tyrosine Hydroxylase rabbit pAb
Alternative Names Tyrosine 3-monooxygenase (EC 1.14.16.2), Tyrosine 3-hydroxylase (TH)
Applications WB; ELISA
Recommended Dilutions WB 1:500–2000, ELISA 1:10000–20000
Immunogen Synthesized peptide derived from human Tyrosine Hydroxylase
Host Species Rabbit
Storage -20°C, 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band 60 kD
Gene ID (Human) 7054
Human Swiss-Prot No. P07101
Species Reactivity Human, Mouse, Rat
Cellular Localization Cytoplasm, perinuclear region, nucleus, axon, cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Phosphorylation at Ser-19 leads to nuclear localization, while phosphorylation at Ser-31 or Ser-40 results in cytosolic distribution (By similarity). Expressed in dopaminergic axons and terminals.

Background

The protein encoded by this gene catalyzes the conversion of tyrosine to dopamine and serves as the rate-limiting enzyme in catecholamine biosynthesis. It plays a critical role in adrenergic neuron physiology. Mutations in this gene are linked to autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been observed (RefSeq, Jul 2008).

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