ELK Biotechnology OSM rabbit pAb
Oncostatin-M( OSM )에 특이적인 토끼 다클론 항체로 IHC, IF, ELISA에 적합. 인간, 랫드, 마우스 반응성. 합성 펩타이드(AA 50-100)로부터 유래. 분비성 사이토카인 연구에 활용 가능. -20°C에서 1년 보관.
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제품명
OSM rabbit pAb
제품 개요
Oncostatin-M (OSM)에 대한 토끼 다클론 항체입니다.
IHC, IF, ELISA 등 다양한 면역학적 분석에 활용할 수 있으며, 인간, 랫드, 마우스 시료에 반응합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | OSM rabbit pAb |
| Alternative Names | Oncostatin-M (OSM) |
| Applications | IHC; IF; ELISA |
| Recommended Dilutions | IHC-p 1:50–200, ELISA 1:10000–20000 |
| Immunogen | Synthetic peptide from human protein at AA range: 50–100 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 5008 |
| Human Swiss-Prot No | P13725 |
| Cellular Localization | Secreted |
| Species Reactivity | Human; Rat; Mouse |
배경 (Background)
This gene encodes a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family of proteins.
The encoded preproprotein is proteolytically processed to generate the mature protein.
This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines.
It also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor, and granulocyte-macrophage colony stimulating factor in endothelial cells.
This gene and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene.
Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
[provided by RefSeq, Jan 2016]
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