ELK Biotechnology Dsg1 rabbit pAb
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| Product name: | Dsg1 rabbit pAb |
| Alternative Names: | Desmoglein-1 (Cadherin family member 4;Desmosomal glycoprotein 1;DG1;DGI;Pemphigus foliaceus antigen) |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000 |
| Immunogen: | Synthetic peptide from human protein at AA range: 30-90 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 160kD |
| GeneID（Human）: | 1828 |
| Human Swiss-Prot No: | Q02413 |
| Cellular localization: | Cell membrane ; Single-pass type I membrane protein . Cell junction, desmosome. |
| Background: | This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015], |
| Species Reactivity: | Human;Mouse;Rat |
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