
ELK Biotechnology EGF rabbit pAb
EGF rabbit pAb는 인간, 생쥐, 랫트에서 반응하는 폴리클로날 항체로, WB, IHC, IF, ELISA에 적합합니다. 고순도 IgG로 1 mg/ml 농도로 제공되며, 세포 성장 및 분화 연구에 활용됩니다. -20°C에서 1년간 안정적으로 보관 가능합니다.
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ELK Biotechnology EGF rabbit pAb
제품 개요
EGF rabbit pAb는 Epidermal Growth Factor(EGF)에 대한 폴리클로날 항체로, 다양한 생물 종에서 반응하며 세포 성장, 분화, 증식 연구에 사용됩니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | EGF rabbit pAb |
| Alternative Names | Pro-epidermal growth factor (EGF) [Cleaved into: Epidermal growth factor (Urogastrone)] |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB 1:500–2000, IHC-p 1:500–200, ELISA 1:10000–20000 |
| Immunogen | Synthetic peptide from human protein at AA range: 1000–1060 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 130 kD |
| GeneID (Human) | 1950 |
| Human Swiss-Prot No | P01133 |
| Cellular Localization | Membrane; Single-pass type I membrane protein |
| Species Reactivity | Human; Rat; Mouse |
Background
This gene encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide. This protein acts as a potent mitogenic factor that plays an important role in the growth, proliferation, and differentiation of numerous cell types. It binds with high affinity to the epidermal growth factor receptor (EGFR). Defects in this gene cause hypomagnesemia type 4, and dysregulation is associated with cancer progression. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [RefSeq, Jan 2016]
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