ELK Biotechnology Cystatin A rabbit pAb
Cystatin A 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 사용 가능. 사람, 쥐, 마우스 시료에 반응. 세포질에 위치하며, 각질형성 및 암 진단 연구에 활용 가능.
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- ES8644-xxxxx (2개 옵션)
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- pk
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Cystatin A rabbit pAb
제품 개요
Cystatin A 단백질을 인식하는 토끼 유래 폴리클로날 항체입니다. 본 항체는 다양한 응용 분야(WB, IHC, IF, ELISA)에 적합하며, 사람, 쥐, 마우스 시료에서 반응성을 보입니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Cystatin A rabbit pAb |
| Alternative Names | Cystatin-A (Cystatin-AS; Stefin-A) |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB 1:500–2000, IHC-p 1:500–200, ELISA 1:10000–20000 |
| Immunogen | Synthetic peptide from human protein at AA range: 60–98 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 11 kDa |
| Gene ID (Human) | 1475 |
| Human Swiss-Prot No. | P01040 |
| Cellular Localization | Cytoplasm |
| Species Reactivity | Human; Rat; Mouse |
Background
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens.
This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer.
[provided by RefSeq, Jul 2008]
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