ELK Biotechnology I-FABP rabbit pAb
인간, 생쥐, 랫트에서 반응하는 I-FABP 단백질에 대한 rabbit polyclonal antibody. WB, IHC, IF, ELISA에 적합하며 고순도 IgG 형태로 제공. 세포질 내 지방산 결합 단백질 연구 및 대사 관련 연구에 활용 가능.
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제품명
I-FABP rabbit pAb
기본 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | Fatty acid-binding protein, intestinal (Fatty acid-binding protein 2; Intestinal-type fatty acid-binding protein; I-FABP) |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB 1:500–2000, IHC-p 1:500–200, ELISA 1:10000–20000 |
| Immunogen | Synthetic peptide from human protein at AA range: 90–132 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 15 kD |
| GeneID (Human) | 2169 |
| Human Swiss-Prot No | P12104 |
| Cellular Localization | Cytoplasm |
| Species Reactivity | Human; Mouse; Rat |
제품 설명
The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types — hepatic, intestinal, and cardiac-type. They form 14–15 kDa proteins and are thought to participate in the uptake, intracellular metabolism, and/or transport of long-chain fatty acids. They may also play roles in the modulation of cell growth and proliferation.
The intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identifies an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance.
[provided by RefSeq, Jul 2008]
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