ELK Biotechnology Histone H3 (Tri-Methyl-K10) rabbit pAb
Histone H3 (Tri-Methyl-K10) rabbit polyclonal antibody for WB and ELISA. Recognizes human, rat, and mouse H3K10me3. High specificity and sensitivity with 1 mg/ml concentration. Stable for 1 year at -20°C.
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Histone H3 (Tri-Methyl-K10) rabbit pAb
제품 개요
Histone H3 (Tri-Methyl-K10) rabbit polyclonal antibody는 히스톤 H3의 라이신 10 삼메틸화(Tri-Methyl-K10) 변형을 인식하는 항체입니다. 핵 내 크로마틴 구조 연구 및 후성유전학 관련 단백질 분석에 활용됩니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Histone H3 (Tri-Methyl-K10) rabbit pAb |
| Alternative Names | H3K10ME3; HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; HIST1H3F; H3FI; HIST1H3G; H3FH; HIST1H3H; H3FK; HIST1H3I; H3FF; HIST1H3J; H3FJ; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l; HIST2H3A; HIST2H3C; H3F2; H3FM; HIST2H3D; Histone H3.2; Histone H3/m; Histone H3/o; H3F3A; H3.3A; H3F3; PP781; H3F3B; H3.3B; Histone H3.3 |
| Applications | WB; ELISA |
| Recommended Dilutions | WB: 1:500–2000, ELISA: 1:10000–20000 |
| Immunogen | Synthetic Tri-Methyl peptide from human protein at AA range: 10 |
| Storage | -20°C / 1 year |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 15 kD |
| GeneID (Human) | 8350 |
| Human Swiss-Prot No | P68431 / Q71DI3 / P84243 / Q6NXT2 |
| Cellular Localization | Nucleus; Chromosome |
| Species Reactivity | Human; Rat; Mouse |
Background
Histones are basic nuclear proteins that form the nucleosome structure of chromosomal fibers in eukaryotes. Each nucleosome consists of approximately 146 bp of DNA wrapped around an octamer composed of pairs of four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted by the linker histone H1 to form higher-order structures. The gene encoding histone H3 is intronless and replication-dependent, located on chromosome 6p22-p21.3, and its transcripts contain a palindromic termination element instead of polyA tails.
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