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ELK Biotechnology Ku-70 (Acetyl Lys317) rabbit pAb
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ELK Biotechnology Ku-70 (Acetyl Lys317) rabbit pAb

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Ku-70 (Acetyl Lys317) rabbit pAb는 DNA 복구 관련 Ku70 단백질의 아세틸화 Lys317 부위를 인식하는 폴리클로날 항체입니다. WB, ELISA, IHC에 적합하며 사람, 생쥐, 랫트 시료에서 반응합니다. 핵 내 Ku 복합체 연구에 유용한 고특이성 항체입니다.

카탈로그번호
ES8631-xxxxx (2개 옵션)
판매단위
pk
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2개 옵션
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ELK Biotechnology ES8631-100UL Ku-70 (Acetyl Lys317) rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES8631-50UL Ku-70 (Acetyl Lys317) rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology Ku-70 (Acetyl Lys317) rabbit pAb

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Ku-70 (Acetyl Lys317) rabbit pAb

기본 정보

항목 내용
Alternative Names X-ray repair cross-complementing protein 6 (EC 3.6.4.-) (EC 4.2.99.-) (5'-deoxyribose-5-phosphate lyase Ku70) (5'-dRP lyase Ku70) (70 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 1) (ATP-dependent DNA helicase II 70 kDa subunit) (CTC box-binding factor 75 kDa subunit) (CTC75) (CTCBF) (DNA repair protein XRCC6) (Lupus Ku autoantigen protein p70) (Ku70) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 6)
Applications WB; ELISA; IHC
Recommended Dilutions WB 1:500–2000; IHC-p 1:50–300; ELISA 1:2000–20000
Immunogen Synthetic Acetyl peptide from human protein at AA range: 317
Host Rabbit
Storage -20°C / 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band 69 kD
GeneID (Human) 2547
Human Swiss-Prot No P12956
Cellular Localization Nucleus, Chromosome
Species Reactivity Human; Rat; Mouse

배경 정보

The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa.
The complex functions as a single-stranded DNA-dependent ATP-dependent helicase and may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination.
High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
[provided by RefSeq, Jul 2008]

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