ELK Biotechnology Histone H2A.Z rabbit pAb
Histone H2A.Z rabbit pAb는 인간, 마우스, 랫트 시료에 반응하는 폴리클로날 항체로, WB 및 ELISA에 적합합니다. 핵 내 염색질 관련 단백질 검출에 사용되며, 합성 펩타이드 항원을 기반으로 제작되었습니다. -20°C에서 1년 보관 가능합니다.
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Histone H2A.Z rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Histone H2A.Z rabbit pAb |
| Alternative Names | Histone H2A.Z (H2A/z) |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:10000–20000 |
| Immunogen | Synthetic peptide from human protein at AA range: 1–30 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 20 kD |
| GeneID (Human) | 3015 |
| Human Swiss-Prot No | P0C0S5 |
| Cellular Localization | Nucleus, Chromosome |
| Species Reactivity | Human, Mouse, Rat |
Background
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone (H1) with DNA between nucleosomes to form higher-order chromatin structures.
This gene encodes a replication-independent member of the histone H2A family, distinct from other members. Studies in mice have shown that this particular histone is required for embryonic development, and lack of functional histone H2A leads to embryonic lethality.
[Provided by RefSeq, Jul 2008]
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