ELK Biotechnology Cytokeratin 14/17 rabbit pAb
Cytokeratin 14/17 rabbit polyclonal antibody for WB and ELISA applications. Recognizes human, mouse, and rat proteins. Targets keratin family involved in epithelial cytoskeleton formation. Long-term storage at -20°C.
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- ES8537-xxxxx (2개 옵션)
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Cytokeratin 14/17 rabbit pAb
제품 개요
Cytokeratin 14/17 rabbit polyclonal antibody는 케라틴 패밀리 단백질을 인식하며, 주로 상피세포의 세포골격 형성 연구에 사용됩니다. 인간, 생쥐, 흰쥐 시료에 반응하며, WB 및 ELISA 분석에 적합합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Cytokeratin 14/17 rabbit pAb |
| Alternative Names | KRT14 |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:10000–20000 |
| Immunogen | Synthetic peptide from human protein (AA range: 261–310) |
| Species Reactivity | Human; Mouse; Rat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 52 kD |
| Gene ID (Human) | 3861 |
| Human Swiss-Prot No | P02533 / Q04695 |
| Cellular Localization | Cytoplasm, Nucleus — expressed in both as a filamentous pattern |
| Storage | -20°C / 1 year |
| Host Species | Rabbit |
Background
This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules (type II keratin). Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11. [provided by RefSeq, Jul 2008]
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