
Thermo Fisher Scientific CSE1L Monoclonal Antibody (2C10)
CSE1L 단백질을 인식하는 Mouse monoclonal antibody (Clone 2C10). Western blot 및 ELISA에서 검증됨. Human 시료에 반응하며, ascites 형태의 unconjugated 액상 제품. -20°C 보관, 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2C10 |
| Immunogen | CSE1L (NP_001307, 872 a.a. – approx. 971 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
LIGLFELPED DTIPDEEHFI DIEDTPGYQT AFSQLAFAGK KEHDPVGQMV NNPKIHLAQS LHKLSTACPG RVPSMVSTSL NAEALQYLQG YLQAARVTLL
Target Information
Proteins carrying a nuclear localization signal (NLS) are transported into the nucleus via the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and releases importin-alpha. The encoded protein binds strongly to NLS-free importin-alpha, a binding released in the cytoplasm by RANBP1 and RANGAP1. This protein may also play roles in apoptosis and cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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