Thermo Fisher Scientific ADRA2C/alpha 2C Adrenergic Receptor Polyclonal Antibody
인간, 마우스, 랫트에서 반응하는 ADRA2C/alpha 2C 아드레날린 수용체 폴리클로날 항체. IHC, ICC, Flow, ELISA 등 다양한 응용에 적합. Rabbit IgG 기반으로 Protein A 정제. 고순도 액상 형태로 -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Flow Cytometry (Flow) | 1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human ADRA2C/alpha 2C Adrenergic Receptor (amino acids 21–120) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily and include three subtypes: alpha2A, alpha2B, and alpha2C. These receptors regulate neurotransmitter release from sympathetic nerves and adrenergic neurons in the central nervous system. Studies in mice indicate that both alpha2A and alpha2C subtypes are required for normal presynaptic control of neurotransmitter release. The alpha2A subtype inhibits transmitter release at high stimulation frequencies, while alpha2C modulates neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which lacks introns in both its coding and untranslated sequences.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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