Thermo Fisher Scientific ANKRD13A Polyclonal Antibody
Rabbit polyclonal antibody against human ANKRD13A. Validated for Western blot and ELISA. Recombinant immunogen (aa 1–240). Supplied in PBS with glycerol, stored at -20°C. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–240 of human ANKRD13A (NP_149112.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.63 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2854801 |
Product Specific Information
Immunogen sequence:
MSSACDAGDH YPLHLLVWKN DYRQLEKELQ GQNVEAVDPR GRTLLHLAVS LGHLESARVL LRHKADVTKE NRQGWTVLHE AVSTGDPEMV YTVLQHRDYH NTSMALEGVP ELLQKILEAP DFYVQMKWEF TSWVPLVSRI CPNDVCRIWK SGAKLRVDIT LLGFENMSWI RGRRSFIFKG EDNWAELMEV NHDDKVVTTE RFDLSQEMER LTLDLMKPKS REVERRLTSP VINTSLDTKN
Target Information
ANKRD13A (also known as ANKRD13) is a 590 amino acid protein containing two ANK repeats and four UIM (ubiquitin-interacting motif) repeats. It localizes to the cell membrane and functions as a ubiquitin-binding protein that specifically recognizes and binds Lys-63–linked ubiquitin, but not Lys-48–linked ubiquitin. ANKRD13A positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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