Thermo Fisher Scientific SH2D1A Monoclonal Antibody (1C9)
Thermo Fisher Scientific의 SH2D1A Monoclonal Antibody (1C9)는 인간 SH2D1A 단백질을 인식하는 mouse IgG2a 형 단일클론 항체입니다. Western blot 및 ELISA에 적합하며, GST 태그가 포함된 full-length recombinant protein을 면역원으로 사용했습니다. 연구용으로만 제공됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 0.3 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1C9 |
| Immunogen | SH2D1A (AAH20732, 1–128 a.a.) full-length recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of SH2D1A protein:
MDAVAVYHGK ISRETGEKLL LATGLDGSYL LRDSESVPGV YCLCVLYHGY IYTYRVSQTE
TGSWSAETAP GVHKRYFRKI KNLISAFQKP DQGIVIPLQY PVEKKSSARS TQGTTGIRED PDVCLKAPTarget Information
The SH2D1A gene encodes a protein with a major role in bidirectional stimulation of T and B cells. It contains an SH2 domain and a short tail, associating with the signaling lymphocyte-activation molecule (SLAM) to inhibit recruitment of SHP-2. It also binds to surface molecules on activated T, B, and NK cells, modulating signal transduction. Mutations in this gene lead to X-linked lymphoproliferative syndrome type 1 (Duncan disease), a rare immunodeficiency associated with susceptibility to Epstein-Barr virus, severe mononucleosis, and malignant lymphoma. Multiple transcript variants encoding different isoforms are known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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