Thermo Fisher Scientific GluR1 Polyclonal Antibody
Goat-derived polyclonal antibody recognizing GluR1 (Human). Validated for Western blot at 0.1–0.3 µg/mL. Liquid form, 0.5 mg/mL concentration, stored at -20°C. Targets both GluR1 isoforms and suitable for research use only.
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Applications
- Western Blot (WB): Tested dilution 0.1–0.3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-KIMQQWKNSDARD (aa 265–277) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933395 |
Product Specific Information
- This antibody is expected to recognize both reported isoforms (NP_000818.2; NP_001107655.1).
- Tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
GluR1 (glutamate receptor 1) is an ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of L-glutamate induces a conformation change that opens the cation channel, converting the chemical signal to an electrical impulse. The receptor then desensitizes rapidly into a transient inactive state with a bound agonist. In the presence of CACNG4, CACNG7, or CACNG8, GluR1 shows resensitization characterized by delayed current flux upon continued glutamate application.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-142749_GluR1_P42261-1_Goat.svg, PA5-142749_GluR1_P42261-1_Goat_PDP.jpeg)
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