Thermo Fisher Scientific GSPT1 Polyclonal Antibody
GSPT1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot에 최적화되어 있습니다. 인간 시료에 반응하며, 합성 펩타이드를 면역원으로 사용했습니다. 액상 형태로 제공되며, -20°C에서 보관 가능합니다.
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Applications
- Western Blot (WB): 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human GSPT1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2609398 |
Product Specific Information
- Peptide sequence: AGGRAAPVES SQEEQSLCEG SNSAVSMELS EPIENGETEM SPEESWEHKE
- Sequence homology: Cow: 93%; Dog: 87%; Human: 100%; Pig: 87%; Rabbit: 100%; Rat: 93%
Target Information
eRF3a (eukaryotic peptide chain release factor subunit 3a), also known as GSPT1 (G1 to S phase transition 1), is a 499 amino acid protein belonging to the GTP-binding elongation factor family. It is involved in regulating cell growth by controlling translation termination. Human eRF3a shares 94% sequence identity with its mouse counterpart, indicating conserved function across species. The gene encoding eRF3a maps to human chromosome 16, which contains over 900 genes and comprises nearly 3% of the human genome. Mutations in the GAN gene on chromosome 16 may lead to giant axonal neuropathy, a nervous system disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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