Thermo Fisher Scientific PSMD11 Polyclonal Antibody
Thermo Fisher PSMD11 Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하며 WB, ICC/IF, ELISA에 적합합니다. Recombinant fusion protein을 면역원으로 사용한 Rabbit IgG 항체로, 액상 형태이며 -20°C 보관이 필요합니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 253–422 of human PSMD11 (NP_002806.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.22 mg/mL |
| Purification | Affinity Chromatography |
| Storage buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2913914 |
Product Specific Information
- Positive test controls: NCI-H460, 293T, Mouse brain, Rat testis
- Localization: Cytoplasm, Nucleus, Cytosol
Immunogen sequence:
YMLLCKIMLN TPEDVQALVS GKLALRYAGR QTEALKCVAQ ASKNRSLADF EKALTDYRAE LRDDPIISTH LAKLYDNLLE QNLIRVIEPF SRVQIEHISS LIKLSKADVE RKLSQMILDK KFHGILDQGE GVLIIFDEPP VDKTYEAALE TIQNMSKVVD SLYNKAKKLT
Target Information
The 26S proteasome (PSMD11) is a multicatalytic proteinase complex composed of a 20S core and a 19S regulator.
- The 20S core has four rings of 28 non-identical subunits (two rings of seven alpha and two rings of seven beta subunits).
- The 19S regulator consists of a base with six ATPase and two non-ATPase subunits, and a lid with up to ten non-ATPase subunits.
Proteasomes are abundant in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal pathway.
The immunoproteasome processes class I MHC peptides.
PSMD11 is a non-ATPase subunit of the 19S regulator.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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