Thermo Fisher Scientific IL-37 Polyclonal Antibody
인간 IL-37에 특이적인 Rabbit Polyclonal Antibody로, IHC(P)에서 1:50–1:200 희석으로 검증됨. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. PBS 버퍼(40% 글리세롤, 0.02% 아지드) 보존, 연구용으로 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human IL-37. Recombinant protein control fragment (Product #RP-96068). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2642700 |
Product Specific Information
- Immunogen sequence:
LYCDKDKGQS HPSLQLKKEK LMKLAAQKES ARRPFIFYRA QVGSWNMLES AAHPGWFICT SCNCNEPVGV TDKFENRKHI EFSFQPVCKA EMSPSE - Highest antigen sequence identity to the following orthologs:
- Mouse: 32%
- Rat: 31%
Target Information
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). It also binds to interleukin 18 binding protein (IL18BP), forming a complex with IL18 receptor beta subunit to inhibit IL18 activity.
This gene, along with eight other interleukin 1 family genes, forms a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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