Thermo Fisher Scientific LIMS1 Polyclonal Antibody
LIMS1 단백질을 인식하는 토끼 다클론 항체로, Western blot과 IHC(P)에서 검증됨. 항원 친화 크로마토그래피로 정제되었으며, 휴먼 시료에 반응. PBS 버퍼와 글리세롤로 안정화되어 장기 보관 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human LIMS1. Recombinant protein control fragment (Product #RP-105173) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2791635 |
Product Specific Information
Immunogen sequence:
MTALQLKELS HSGLYRRRRD RPDSLRVNGL PEEELSNMAN AL
Target Information
The protein encoded by this gene is an adaptor protein containing five LIM domains (double zinc fingers). It is likely involved in integrin signaling through LIM domain-mediated interaction with integrin-linked kinase in focal adhesion plaques. The protein may act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which participates in growth factor receptor kinase signaling pathways. Localization to the periphery of spreading cells suggests a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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