Thermo Fisher Scientific TFF3 Polyclonal Antibody
Rabbit polyclonal antibody against Human TFF3 protein. Suitable for IHC (P) and ICC/IF applications. High specificity and affinity purified. Provided in liquid form with PBS/glycerol buffer. For research use only.
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Thermo Fisher Scientific TFF3 Polyclonal Antibody
Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:5,000–1:10,000
- Immunocytochemistry (ICC/IF): 0.25–2 µg/mL
Publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TFF3. Recombinant protein control fragment (Product # RP-95294) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2648411 |
Product Specific Information
- Immunogen sequence:
SSAEEYVGLS ANQCAVPAKD RVDCGYPHVT PKECNNRGCC FDSRIPGVPW CFKPLQEAECT - Highest antigen sequence identity to orthologs:
- Mouse: 74%
- Rat: 74%
Target Information
Trefoil peptides are protease-resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intrachain disulfide bonds forming the trefoil motif (P-domain) and are clustered in human chromosome 21q22.3.
Trefoil Factor 3 (TFF3) is one of three trefoil peptides secreted by epithelial cells lining mucus membranes in the intestines and respiratory tract. TFF3 acts mainly as a disulfide-linked homodimer and may promote cell migration during healing processes. It is involved in the maintenance and repair of the intestinal mucosa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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