Thermo Fisher Scientific eIF4A3 Polyclonal Antibody
Rabbit polyclonal antibody targeting human eIF4A3, validated for WB, IHC(P), and ICC/IF. Detects endogenous total eIF4A3. Supplied as liquid, unconjugated, affinity-purified, in PBS with glycerol. Suitable for research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EIF4A3 (Accession P38919), corresponding to amino acid residues L293–V343 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899804 |
Product Specific Information
Antibody detects endogenous levels of total eIF4A3.
Target Information
eIF4A3 is a member of the DEAD box protein family, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD). These proteins are putative RNA helicases involved in various cellular processes that alter RNA secondary structure, including translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly.
Based on distribution patterns, some members of this family are believed to participate in embryogenesis, spermatogenesis, and cellular growth and division.
eIF4A3 is a nuclear matrix protein with an amino acid sequence highly similar to translation initiation factors eIF4AI and eIF4AII, other members of the DEAD box family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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