Thermo Fisher Scientific MYOT Monoclonal Antibody (OTI8A7), TrueMAB
MYOT 단백질을 인식하는 Mouse monoclonal 항체로, Western Blot에 최적화되어 있습니다. Human, Mouse, Rat 시료에 반응하며, E.coli에서 발현된 full-length MYOT 단백질을 면역원으로 사용했습니다. 동결건조 형태로 제공되며, 연구용으로 적합합니다.
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Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8A7 |
| Immunogen | Full length human recombinant protein of human MYOT produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The MYOT gene encodes a cytoskeletal protein involved in maintaining thin filament stability during muscle contraction. It binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene are linked to limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants exist, though the full-length nature of some remains undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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