Thermo Fisher Scientific CHRNA7 Polyclonal Antibody
인간, 생쥐, 랫트 반응성의 CHRNA7 폴리클로날 항체로 다양한 면역실험(WB, IHC, ICC, ELISA)에 적합. Rabbit IgG 기반으로 Protein A로 정제된 액상 형태. 고농도(1 mg/mL)이며 -20°C 보관. 신경전달 관련 CHRNA7 단백질 연구용으로 사용.
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Thermo Fisher Scientific CHRNA7 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:400 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human CHRNA7, amino acids 441–502 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Chromosome 15 encodes over 700 genes and comprises nearly 3% of the human genome. CHRFAM7A, a fusion protein comprised of FAM7A and AChR alpha7, is encoded by the CHRFAM7A gene, which is located on a region of human chromosome 15 associated with several neuropsychiatric disorders such as schizophrenia and bipolar affective disorder.
CHRFAM7A, also known as D-10 or CHRNA7, is a 412 amino acid multi-pass membrane protein belonging to the nicotinic acetylcholine receptor (nAChR) subfamily of ligand-gated ion channel proteins. This protein family mediates signal transmission at synapses and CHRFAM7A is expressed in the hippocampus. Alternative splicing of the CHRFAM7A gene produces two splice variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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