Thermo Fisher Scientific Phospho-GSK3 beta (Ser9) Monoclonal Antibody (7A4)
Phospho-GSK3β (Ser9) 단일클론 항체로 인간 GSK3β 인산화 형태를 특이적으로 인식. Western blot, IHC, ICC, Flow cytometry 등 다양한 응용 가능. 고농도(1 mg/mL) 액상 형태로 -20°C 보관. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:200 |
| Flow Cytometry (Flow) | 1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 7A4 |
| Immunogen | Synthetic peptide derived from human GSK3 beta (Ser 9), around 1–50aa (phospho Ser 9) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
Target Information
GSK3B is a proline-directed serine/threonine protein kinase involved in energy metabolism, neuronal cell development, and body pattern formation. It negatively regulates glucose homeostasis and participates in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways.
GSK3B is a critical component of the Wnt/beta-catenin signaling pathway, where its activity inhibits Wnt signaling by promoting beta-catenin degradation. It is also involved in Hedgehog, Notch, and insulin signaling pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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