Thermo Fisher Scientific LRWD1 Polyclonal Antibody
LRWD1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 세포 주기 G1/S 전이 연구 및 ORC 복합체 안정성 분석에 유용하며, 비결합(Unconjugated) 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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- PA5112091
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunoprecipitation (IP) | 0.2–1 µL/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the center region of the Human LRWD1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2866827 |
Target Information
Required for G1/S transition. Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish the pre-replication complex (preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Interacts with histone H3 and H4 trimethylation marks (H3K9me3, H3K27me3, and H4K20me3) cooperatively with DNA methylation. Required for silencing of major satellite repeats and may be important for ORC2, ORC3, and ORC4 stability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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