Thermo Fisher Scientific Neuropilin 1 Polyclonal Antibody
Thermo Fisher Scientific의 Neuropilin 1 Polyclonal Antibody는 사람, 생쥐, 쥐 시료에 반응하며 IHC(P) 실험에 적합합니다. 단백질 A로 정제된 0.5 mg/mL 액상 항체로, Neuropilin 1 단백질(아미노산 813–839)을 면역원으로 사용합니다. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Range of amino acids 813–839 of rat Neuropilin 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2540830 |
Product Specific Information
Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM sodium citrate buffer, pH 6.0 for 10–20 minutes, followed by cooling at room temperature for 20 minutes.
Target Information
Neuropilin 1 is a 923 amino acid membrane-bound coreceptor belonging to the neuropilin family, containing two CUB domains, two F5/8 type C domains, and a MAM domain.
It forms a heterodimer with Neuropilin 2 (NRP2) and binds to plexin (PLXNB1) to form semaphorin receptors.
Expressed predominantly in the nervous system, Neuropilin 1 plays roles in cardiovascular development, angiogenesis, axon guidance, neuronal circuit formation, cell survival, neuronal migration, and organogenesis.
It functions as a receptor for semaphorins and VEGF, regulating VEGF-induced angiogenesis.
Neuropilin 1 may be involved in aggressive prostate carcinoma and breast cancer progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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