Thermo Fisher Scientific ABCB1 Monoclonal Antibody (OTI2G7), TrueMAB
인간 ABCB1 단백질(아미노산 347-710)을 인식하는 마우스 단클론 항체입니다. Western blot에 1:1,000 희석으로 사용 가능하며, 친화 크로마토그래피로 정제되었습니다. PBS/BSA/glycerol 완충액에 보관하며 -20°C에서 안정적으로 유지됩니다.
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2G7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 347–710 of human ABCB1 produced in SF9 cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters.
ABC proteins transport various molecules across extra- and intra-cellular membranes.
ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).
This protein is a member of the MDR/TAP subfamily and is involved in multidrug resistance.
It functions as an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity, responsible for decreased drug accumulation in multidrug-resistant cells and often mediates resistance to anticancer drugs.
Additionally, this protein acts as a transporter in the blood-brain barrier.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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