
Thermo Fisher Scientific Lodelcizumab Humanized Recombinant Human Monoclonal Antibody
인간 PCSK9을 타겟으로 하는 인간화 재조합 단일클론 항체. ELISA 등 연구용으로 적합하며 높은 특이성과 순도를 제공. CHO 세포에서 발현된 IgG1, kappa 형 항체로 Protein A로 정제됨. 장기 보관 시 -20°C 이하에서 안정적 유지 가능.
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Applications
- ELISA (ELISA)
Tested Dilution: 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Human / IgG1, kappa |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Immunogen | Human PCSK9 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911140 |
Product Specific Information
- Endotoxin level < 0.01 EU/µg by LAL method
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Store at 2–8°C for one week.
- Store at -20 to -80°C for twelve months from the date of receipt.
Target Information
Lodelcizumab is a biosimilar that targets PCSK9.
PCSK9 is a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family.
This protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum.
It plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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