Thermo Fisher Scientific CCR8 Polyclonal Antibody
CCR8 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 polyclonal 항체. Western blot 및 IHC(P) 검증 완료. 항원 친화 크로마토그래피로 정제된 액상형 제품으로, 인간 시료에 반응. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide CYSFYNQQTLK corresponding to the second extracellular domain sequence of human CCR8 (aa 183–193) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M potassium phosphate with 0.14M NaCl, 0.1% BSA |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_1954701 |
Product Specific Information
- Recommended positive controls: Human K562 cells (ICC) and human spleen (IHC-P)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
Target Information
CCR8 encodes a member of the beta chemokine receptor family, predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors play essential roles in cell migration to inflammatory sites. CCR8 is preferentially expressed in the thymus, with ligands including I-309, TARC, and MIP-1β. The receptor is involved in monocyte chemotaxis, thymic cell apoptosis, and positioning of activated T cells in lymphoid tissues. CCR8 expression has been reported in spleen, thymus, NK cells, monocytes, and T cells, with lower levels in peripheral blood leukocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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